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Evolution Explained The most fundamental notion is that all living things alter over time. These changes help the organism survive, reproduce or adapt better to its environment. Scientists have used genetics, a brand new science, to explain how evolution happens. They also have used the science of physics to calculate how much energy is needed for these changes. Natural Selection In order for evo

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Intrauterine growth restriction (IUGR) is a leading cause of neonatal morbidity and mortality in humans and domestic animals. Developmental adaptations of skeletal muscle in IUGR lead to increased risk of premature muscle loss and metabolic disease in later life. Here, we identified β-Klotho (KL, a fibroblast growth factor 21 (FGF21) co-receptor, as a novel regulator of muscle development in IUGR. Using the pig as a naturally-occurring disease model, we performed transcriptome-wide profiling of fetal muscle (day 90 of pregnancy) from IUGR