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© 2020 John Wiley Sons A/S. Published by John Wiley Sons Ltd.Osteosclerotic metaphyseal dysplasia (OSMD) is an uncommon autosomal recessive sclerosing skeletal dysplasia. We report on a 34-year-old client with sandwich vertebrae, platyspondyly, osteosclerosis of this tubular bones, pathologic fractures, and anemia. In the third ten years, he developed osteonecrosis regarding the jaws, which was progressive in spite of repeated surgical treatment over a period of 11 many years. An iliac crest bone b

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The spectroscopic quantification of mixture compositions usually requires pure compounds and mixtures of known compositions for calibration. Since they are not always available, methods to fill such gaps have evolved, which are, however, not generally applicable. Therefore, calibration can be extremely challenging, especially when multiple unstable species, for example, intermediates, exist in a system. This study presents a new calibration approach that uses ab initio molecular dynamics (AIMD)-simulated spectra to set up and calibrat