https://www.selleckchem.com/pr....oducts/mitomycin-c.h
Despite continuous updates of the human reference genome, there are still hundreds of unresolved gaps which account for ~5% of the total sequence length. Given the availability of whole genome de novo assemblies, especially those derived from long-read sequencing data, gap-closing sequences can be determined. By comparing 17 de novo long-read sequencing assemblies with the human reference genome, we identified a total of 1,125 gap-closing sequences for 132 (16.9% of 783) gaps and added up to 2.2 Mbp novel sequences to the human refe
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