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The need to cope with life concerns may drive an individual to resort to high-risk behaviours. This study aimed to determine the relationship between health concerns and high-risk behaviours. A cross-sectional study. We sampled 926 Medical Sciences' students from the North of Iran from September-December 2017 using the stratified sampling method. The most and less common high-risk behaviour was physical inactivity (97.5%) and high-risk sexual behaviour (15.7%), respectively. In multivariate logistic regression analysis, participants' conc