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Our outcomes claim that alteronol causes cyto-protective autophagy in melanoma cells through inhibition of Akt/mTOR pathway, therefore attenuates apoptosis and promotes melanoma cell EMT through TGF-β/Smad3 pathway. Fusion with alteronol and autophagy inhibitor 3-MA is a potential treatment plan for melanoma since it not merely significantly inhibited cyst growth but also suppressed tumor intrusion and migration as anti-metastasis agent.Serotonin neurotransmission may influe
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