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Antimalarial studies showed the highest activity in the group administered with 400 mg/kg + 25 mg chl./kg b/w. In conclusion, A. spicatus was non-toxic at doses less than 1000 mg/kg and significantly reduced parasitemia count in P. berghei infected mice, thus validating its folkloric usage. The online version contains supplementary material available at 10.1007/s43188-020-00070-1. The online version contains supplementary material available at 10.1007/s43188-020-00070-1.This study aimed to obtain necessary toxicological data using experimen
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