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Moreover, the CDs for the first time allow in situ labeling of LDs and epidermal cell membranes simultaneously in live zebrafish. This work expands the diversity for optical properties and applications of CDs, facilitating the design of new LDs-targeting CDs.Novel methods that enable facile, ultrasensitive and multiplexed detection of low molecular weight organic compounds such as metabolites, drugs, additives, and organic pollutants are valuable in biomedical research, clinical diagnosis, food safety and environmental monitoring. Here,