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These genes were mainly involved in cell proliferation and cell cycle. Among them, 15 genes including were found to be strongly associated with the PPI network. We further performed immunohistochemistry, qRT-PCR and Western blotting to identify that expression was higher in CRC than in paired normal tissues. Moreover, in vitro and in vivo experiments demonstrated could promote the proliferation, invasion and migration of colorectal cancer cells. could be considered as a potential biomarker for CRC patients. GINS1 could be considered as

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The objective of this study was to evaluate estrous detection using a physical activity and rumination monitoring system in a seasonal calving organic grazing (GRAZ) and a low-input conventional (ZEROGRAZ) dairy herd. The study was conducted from June 2014 to August 2017. During each breeding season, physical activity and rumination were monitored electronically using an activity and rumination monitoring system (HR-LD tags; SCR Engineers Ltd., Netanya, Israel). Signals resulting from the activity and rumination monitoring system for in