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This study identifies acquired hemopexin deficiency as a risk factor of AKI in SCD and hemopexin replacement as a potential therapy. Copyright © 2020 American Society of Hematology.We used coarse-grained molecular dynamics simulations to characterize the global and local mechanical properties of a DNA origami triangle nanostructure. The structure presents two metastable conformations separated by a free energy barrier that is lowered upon omission of four specific DNA staples (defect). In contrast, only one stable conf

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The realization of lanthanide-doped upconversion nanocrystals embedded in a robust and transparent solid medium is highly desired to achieve deep UV (45cm-1) at ∼290nm can be obtained.Herein, planar laser-induced fluorescence (PLIF) is used in combination with shadowgraphy to study water-droplet aerobreakup. The acquired shadowgraph data are in agreement with previous visualization studies but differ from the PLIF results, yielding new insights into the fragmentation process. In particular, the PLIF data reveal changes in droplet topolog