https://www.selleckchem.com/pr....oducts/nvp-dky709.ht
Atogepant is a selective, oral calcitonin gene-related peptide receptor antagonist in development for preventive treatment of migraine. This randomized, double-blind, phase 1 crossover study evaluated the cardiac repolarization effect of a single supratherapeutic (300 mg) atogepant dose vs placebo in healthy adults. Moxifloxacin 400 mg was the open-label active control. The primary end point was a change from baseline in Fridericia-corrected QT intervals (ΔQTcF). Sixty participants were randomized to atogepant 300 mg, placebo, and mo

https://www.selleckchem.com/pr....oducts/avelestat-azd
4 times for Neisseria spp, 1.6 timesfor Lactobacillus spp (p less then 0,05). The aim To evaluate the efficacy of endoscopic variceal band ligation (EVL) after the first esophageal EVL session in children with PH according to endoscopic data. Materials and methods EVL was performed to 39 patients with PH for the purpose of variceal bleeding primary and secondary prophylaxis. Results Esophageal varices grade decrease was observed in 22 (56.41%) children. Cases of early rebleeding (within 14 days after EVL) were not registered.