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Long non-coding RNA Sox2 overlapping transcript (SOX2OT) was reported to be involved in progression of multiple cancers. However, the role and mechanism of SOX2OT in multiple myeloma (MM) has yet to be unravelled. In the present study, elevated SOX2OT levels are reported in MM cell lines and patient samples as compared to normal plasma cells (nPCs) and healthy donors, respectively. Knock-down of SOX2OT led to a significant inhibition of cell proliferation, arrested cells at G0/G1 phase and induced cell apoptosis in MM samples in vitro, a

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What to Look For in a Lightweight Single Stroller The best lightweight single strollers combine full size comforts with compact convenience. They are easy to fold and carry, and they are easy to stow, and can be tucked away in tight spaces such as the trunk of your car or even narrow door frames. The most recent strollers come with tri-fold designs that make them even smaller. Some meet the requirements of airlines, like gate-checking and cabin storage during flights. Easy to put together For