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The proteinase activity of P. gingivalis had been inhibited because of the PACs recommending that they may exert beneficial effects by decreasing proteolytic degradation associated with the epithelial tight junctions. Legislation of gingival fibroblast inflammatory reactions are a great way to avoid and manage periodontal disease development and extent. We revealed that PACs significantly decrease IL-6 and IL-8 release by P. gingivalis-stimulated gingival fibroblasts. The present research reveale

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