https://art558inhibitor.com/ne....urovascular-area-fla
JIB-04 is a small molecule that pan-selectively inhibits KDMs, showing maximal inhibitory activity against KDM5A, so that as additional targets, KDM4D/4B/4A/6B/4C. Recently, it was discovered that JIB-04 also potently and selectively blocks HIV-1 Tat expression, transactivation, and virus replication in T cellular outlines via the inhibition of a fresh target, serine hydroxymethyltransferase 2. Pharmacokinetic characterization and an analytical means for the quantification of JIB
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