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Influences of these BPs regarding the cellular growth and expansion of RAW 264.7 were also examined so that you can figure out cytotoxicity. The outcomes showed that PIDP significantly inhibited the RANKL-induced osteoclast development in a dose-dependent manner without inducing cytotoxicity beneath the focus of 12.5 μM. It exerted remarkable suppressive impacts from the development of actin bands, the bone tissue resorption, additionally the expressions of osteoclastogenes
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