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The identified miRNAs in present study laid a foundation to understand the Fe-deficiency adaptive mechanisms in citrus plants. The online version contains supplementary material available at 10.1007/s13205-021-02669-z. The online version contains supplementary material available at 10.1007/s13205-021-02669-z.The potential of urate oxidase (uricase) for clinical use has been highlighted because of its role in lowering the blood uric acid levels for the treatment of tumor lysis syndrome. In the present study, the codon-optimize

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