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Up to now, only 2 kinds of archaeocins tend to be known (i) sulfolobicins, produced by the extremely thermophilic Sulfolobus spp. and (ii) haloarcheocins, made by halophilic archaea. Haloarcheocins were initially discovered within the 1980s, but most of their characterisation had been solely predicated on supernatant-based assays. Only a few had been successfully purified and sequenced, as well as fewer have a proposed biosynthetic model. Additionally, their mode