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Interestingly, morphologic evaluation of this cortex shows reduced apoptosis following RIPK1 inhibition. Consistent with this, RIPK1 inhibition decreases the amount of both caspase-3 and caspase-7 activation. Additionally, this protection appears separate of additional inflammatory mediators. Collectively, these findings demonstrate that the necroptotic necessary protein RIPK1 modifies caspase-3/-7 task, finally resulting in reduced neuronal apoptosis. These conclusions hence modify the traditi
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