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01; 95% confidence interval -4.20 to -1.83; p0.001). Median length of stay was 2.61h for the TPI group and 4.63h for the control group (p0.001). More patients in the control group (47.4%) were discharged home with an opioid compared with the TPI group (2.9%) (p0.001). TPI is an effective method for managing myofascial pain in the emergency department. This study indicates it may improve pain compared with conventional methods, reduce length of stay in the emergency department, and reduce opioid prescriptions on discharge. TPI

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vascular disease prior to invasive hemodynamic testing. © The Author(s) 2020.Background Acute right heart failure (RHF) is the main cause of death in patients with acute pulmonary embolism and emergent pulmonary hypertension. However, the molecular mechanisms underpinning the acute RHF and the interactions between the right (RV) and left ventricles (LVs) under the diseased condition remain unknown. Methods and results The Sprague Dawley male rats were randomly divided into the normal control, sham, and pulmonary artery banding