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Somatic mutations in the telomerase reverse transcriptase (TERT) promoter regions are frequent events in urothelial cancer (UC) and their detection in urine (supernatant cell-free DNA or DNA from exfoliated cells) could serve as putative non-invasive biomarkers for UC detection and monitoring. However, detecting these tumor-borne mutations in urine requires highly sensitive methods, capable of measuring low-level mutations. In this study, we developed sensitive droplet digital PCR (ddPCR) assays for detecting TERT promoter mutations (C22

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How to Buy a Cheap Double Mattress It is important to think about your personal preferences when shopping for a mattress. This can include your preferred sleeping position as well as body weight and disposable income. Prices for mattresses can vary from less than 100 pounds up to several thousand pounds. They also depend on the type of materials and the trial period and warranty. Cost Mattresses are a significant investment, and not all are made equal. A good mattress can improve the quality of slee