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Currently, there are no standardized methods for quantitatively measuring fracture repair. Physicians rely on subjective physical examinations and qualitative evaluation of radiographs to detect mineralized tissue. Since most fractures heal indirectly through a cartilage intermediate, these tools are limited in their diagnostic utility of early repair. Prior to converting to bone, cartilage undergoes hypertrophic maturation, characterized by deposition of a provisional collagen X matrix. The objective of this study was to characterize th
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