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ve measures of COVID-19 infection to combat against disease transmission and environmental pollution. The online version of this article (10.1007/s10668-020-01151-9) contains supplementary material, which is available to authorized users. The online version of this article (10.1007/s10668-020-01151-9) contains supplementary material, which is available to authorized users.The accurate determination of the nonpolar surface area of glycans is vital when utilizing liquid chromatograph/mass spectrometry (LC-MS) for structural characterizat

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Intratumor molecular heterogeneity is a key feature of tumorigenesis and is linked to treatment failure and patient prognosis. Here, we aimed to determine what drives tumor cell evolution by performing single-cell transcriptomic analysis. We analyzed 46 hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA) biopsies from 37 patients enrolled for interventional studies at the NIH Clinical Center, with 16 biopsies collected before and after treatment from 7 patients. We developed a novel machine learning-based consensus