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Background Despite current guidelines, a significant increase in the use of core needle biopsy (CN has been noted. Our aims were to determine the profile of patients referred for image-guided biopsies, to assess the diagnostic yield of these biopsies, and to learn whether CNB is an effective alternative to surgical excisional biopsy (SE. Patients and methods All lymph node biopsy samples evaluated in the Department of Pathology and Laboratory Medicine from 2014 to 2017 were included. Patients' demographics, biopsy type, and final d

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These findings demonstrate that loss of GBA function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation, thereby providing a mechanistic basis for the increased PD risk associated with GBA deficiency.Body image disturbance (BID) is implicated in the etiology, maintenance, and relapse of the eating disorders, and remains challenging to treat. New paradigms such as virtual reality (VR) may offer an ecologically viable method to assess and treat BID. This pilot study aimed to determine if a