https://www.selleckchem.com/pr....oducts/phorbol-12-my
We study the diffusive behavior of biased Brownian particles in a two dimensional confined geometry filled with the freezing obstacles. The transport properties of these particles are investigated for various values of the obstacle density η and the scaling parameter f, which is the ratio of work done to the particles to available thermal energy. We show that, when the thermal fluctuations dominate over the external force, i.e., small f regime, particles get trapped in the given environment when the system percol

https://www.selleckchem.com/pr....oducts/sb-204990.htm
Our findings shed light on new mechanisms for how mechanical force regulates the biology of exosomes and bone metabolism.In a recent publication in Nature, Fane et al. establish WNT5A as a central, age-sensitive regulator of the dormancy-to-reactivation axis of melanoma. They show that aged fibroblasts in the lungs suppress WNT5A signaling induced at the primary tumor site to awaken dormant melanoma cells and promote the outgrowth of metastases.In contrast to normal type I collagen (Col1) heterotrimer (α1/α2/α1) produced by fibroblast