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48. The area under the summary receiver operator characteristic curve was 0.76 (95% CI, 0.72-0.79), indicating that circRNAs exhibited a moderate diagnostic value for female reproductive system diseases and may function as potential diagnostic biomarkers. However, further studies are required to verify the clinical applications of circRNAs. Copyright © Ding et al.Since the discovery of the senescence-associated secretory phenotype, the role of senescent hepatic stellate cells (HSCs) in hepatocellular carcinoma (HCC) development has gaine

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These results expanded our knowledge of mammalian gut microbiota within different influencing factors and microbial-related biological features in swine, which contributes to improving animal production and assisting animal model research.This study determined absolute transporter protein abundances in isolated microvessels of human noncancerous cerebral cortex as well as brain metastases of patients with lung and breast cancer, using a validated targeted proteomics approach. As compared with those in microvessels of noncancerous cerebral