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Besides, Dp3-Sam downregulated the mRNA expression of HMG-CoA reductase (HMGCR), sterol regulatory element-binding protein-1 c (SREBP-1 C), fatty acid synthase (FASN), and acetyl-CoA carboxylase (ACC) and upregulated the mRNA expression of cholesterol 7α-hydroxylase (CYP7A1), carnitine palmitoyltransferase1 (CPT1), acyl-coenzyme A oxidase (ACOX), and peroxisome proliferator-activated receptor alpha (PPARα). Dp3-Sam up-regulated the expression of phosphorylation of AMP-activated protein kinase (pAMPK) in HFD-fed rats. Our findings indica

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Winter coats are essential garments designed to provide warmth and protection during cold weather. Made from materials like wool, down, or synthetic insulation, they help retain body heat in freezing temperatures. Popular styles include puffer jackets, parkas, and peacoats, each offering varying levels of insulation and weather resistance. Many coats feature additional elements like hoods, water-resistant fabrics, and thermal linings for extra comfort. Choosing a winter coat depends on the climate and activity level, with lighter coats suited for mild winters a