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Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis, characterized by painful and erythematous papules, pustules or vesicles that rapidly become ulcerative and necrotic. These ulcers have multiple sub-types and can develop anywhere on the body. There are different postulations as to the mechanisms of development for each sub-type. More than half of patients with PG have an underlying disease, with the highest prevalence being inflammatory bowel disease (IBD), followed by inflammatory arthritis and hematological disorders

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Diablo 4 Item Upgrades Item upgrades are upgrade elements that can be put into armor, weapons or trinkets to provide a bonus. They are usually more expensive and require that the item be of an appropriate rank. Upgrades are not usually worth the cost for items that have high requirements. This is particularly relevant for items such as eth Titans that don't have much variation. Glyphs A