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Carotenoids are lipid-soluble yellow to orange pigments produced by plants, bacteria, and fungi. They are consumed by animals and metabolized to produce molecules essential for gene regulation, vision, and pigmentation. Cave animals represent an interesting opportunity to understand how carotenoid utilization evolves. Caves are devoid of light, eliminating primary production of energy through photosynthesis and, therefore, limiting carotenoid availability. Moreover, the selective pressures that favor carotenoid-based traits, like pigment

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Zn had been discovered to regulate the expression of peroxidases (peroxiredoxin-1, peroxiredoxin-5, peroxiredoxin-6) to ease AFB1-induced oxidative tension. More over, Zn could reduce steadily the appearance of pro-apoptotic genes (cleaved-caspase-3, caspase-9, and Bax) and increase the appearance of anti-apoptotic genes (Bcl-2 and Bcl-xl) to alleviate the cellular apoptosis induced by AFB1. In inclusion, AFB1 paid off intracellular ATP amounts, whereas Zn supplementation boost