https://www.selleckchem.com/pr....oducts/picropodophyl
BACKGROUND CD47 is a broadly expressed cell surface glycoprotein associated with immune evasion. Interaction with the inhibitory receptor signal regulatory protein alpha (SIRPα), primarily expressed on myeloid cells, normally serves to restrict effector function (eg, phagocytosis and immune cell homeostasis). CD47/SIRPα antagonists, commonly referred to as 'macrophage checkpoint' inhibitors, are being developed as cancer interventions. SRF231 is an investigational fully human IgG4 anti-CD47 antibody that is currently under

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90; CI 95%, 1.62-21.5, and serum potassium ≤3.5mmol/L during hospitalization (OR, 4.97; CI 95%, 1.51-16.36). The Tisdale Score is not a useful tool to stratify hospitalized non-critical COVID-19 patients based on their risks of developing QT interval prolongation. Clinicians should initiate continuous cardiac monitoring for patients who present with a history of ESRD, QTc ≥450ms on admission or serum potassium ≤3.5mmol/L. The Tisdale Score is not a useful tool to stratify hospitalized non-critical COVID-19 patients based on their risk