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Dendritic cells (DC) are key sentinels of the host immune response with an important role in linking innate and adaptive immunity and maintaining tolerance. There is increasing recognition that DC are critical determinants of initiating and sustaining effective T-cell-mediated anti-tumor immune responses. Recent progress in immuno-oncology has led to the evolving insight that the presence and function of DC within the tumor microenvironment (TME) may dictate efficacy of cancer immunotherapies as well as conventional cancer therapies, i

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The world's poorest countries were hit hardest by COVID-19 due to their limited capacities to combat the pandemic. The urban water supply and water consumption are affected by the pandemic because it intensified the existing deficits in the urban water supply and sanitation services. In this study, we develop an integrated spatial analysis approach to investigate the impacts of COVID-19 on multi-dimensional Urban Water Consumption Patterns (UWCPs) with the aim of forecasting the water demand. We selected the Tabriz metropolitan area as a c