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The impact of the coronavirus disease 2019 (COVID-19) pandemic on pediatric emergency department (ED) visits is not well characterized. We aimed to describe the epidemiology of pediatric ED visits and resource use during the pandemic. We conducted a cross-sectional study using the Pediatric Health Information System for ED visits to 27 US children's hospitals during the COVID-19 pandemic period (March 15, 2020, to August 31, 202 and a 3-year comparator period (March 15 to August 31, 2017-2019). ED visit rates, patient and visit charac

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As a proof of concept, the sensitive and selective detection of p53 gene, Hg2+, and adenosine with the assistance of Ti3C2 nanosheets-based fluorescence sensing nanoplatform were successfully realized. Moreover, it is also applicable for the evaluation the level of these analytical targets in real samples. By simply switching the recognition sequences of DNA probe, the universal sensing strategy could also be applied for detecting many other types of targets. The simple and universal sensing nanoplatform is expected to promote wide a