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The comparison of the proposed approach with state-of-the art proves the importance of the used criteria in the context of MC delineation, towards a better management of breast cancer. Graphical Abstract Flowchart of the proposed approach.Melanoma is one of the most dangerous skin cancers. The current melanoma segmentation is mainly based on FCNs (fully connected networks) and U-Net. Nevertheless, these two kinds of neural networks are prone to parameter redundancy, and the gradient of neural networks disappears that occurs when the ne