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Serving as guest editor of this issue on youth mental health for the North Carolina Medical Journal has greatly expanded the breadth and depth of my understanding of the aforementioned issues relevant for today's youth. I hope that this issue is as informative to your work, regardless of your role in serving and advocating for young people in the great state of North Carolina. ©2020 by the North Carolina Institute of Medicine and The Duke Endowment. All rights reserved.BACKGROUND Health care costs are on the rise and causing financial

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This study evaluated the antibacterial activity of colloidal platinum nanoparticles (CPNs) toward Streptococcus mutans (S. mutans) viability. S. mutans 109c was treated with water and three CPN solutions at 37°C for 24 h (i.e., control, PAA-Pt, C-Pt, C-CyD-Pt). Dilution series (10-1-10-5) were prepared using brain heart infusion (BHI) broth for all samples, and a 100 µL suspension of each dilution was spread onto a BHI agar plate. Colony-forming units (CFU/mL) were determined after 24 h. The effects of CPNs on S. mutans survival and bio