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Although previous studies have made significant contributions to establishment animal traumatic brain injury (TBI) models for simulation of human TBI, the accuracy, controllability, and modeling efficiency of animal TBI models need to be further improved. This study established a novel high-efficiency graded mice TBI model induced by shock wave. A total of 125 mice were randomly divided into sham, 0.7mm, 0.6mm, and 0.5mm group according to the depth of the cross groove of the aluminum sheets. The stability and repeatability of

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