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https://www.selleckchem.com/pr....oducts/napabucasin.h
ials are needed to evaluate epilepsy surgery targeting cortex involved in the first 3-10 seconds of ictus.Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gut. GISTs are thought to arise solely from interstitial cells of Cajal (ICC), a KIT-positive population that controls gut motility. Activating gain-of-function mutations in KIT and PDGFRA are the most frequent driver events, and most of these tumors are responsive to the tyrosine kinase inhibitor imatinib. Less common drivers include mutant BRA
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