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Local delivery of antimicrobials for otitis media treatment would maximize therapeutic efficacy while minimizing side effects. However, drug transport across the tympanic membrane in the absence of a delivery system is challenging. In this study, the MSlys endolysin was encapsulated in deformable liposomes for a targeted treatment of S. pneumoniae, one of the most important causative agents of otitis media. MSlys was successfully encapsulated in liposomes composed of l-alpha-lecithin and sodium cholate (51) or

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technologies evolve, the FBI may continue to be refined to address parents' most relevant concerns. We aimed to evaluate respiratory impacts on static and respiratory gated (RG) Tc-MAA SPECT in terms of respiratory motion (RM) blur, attenuation correction (AC), and volume-of-interest (VOI) segmentation on lung shunt faction (LSF) and tumor-to-normal liver ratio (TNR) estimation for liver radioembolization therapy planning. The XCAT phantom was used to simulate a population of 300 phantoms, modeling various anatomical variations, tumor c