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1 vs. 6.9, P=0.021). Risk of pouch failure is increased in patients who develop pelvic sepsis after the primary procedure with the largest study demonstrating a four-fold increased risk (hazard ratio 3.691, P0.0001). A final diagnosis of Crohn's causes a four-fold increased risk of pouch failure (n=81; OR 3.92, 95% CI 1.1-15.9, P=0.04). In patients undergoing revisional surgery, improved outcomes are observed but are inferior compared to primary IPAA patients. Pelvic sepsis after primary IPAA and a final diagnosis of Crohn's are ass