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The results proved that the MPTENUE achieved better noise robustness and effectively avoided the curse of dimension; meanwhile, the accuracy and sensitivity can reach 96.9% and 99.2%, respectively.The blood pressure (BP) cuff can be used to modulate blood flow and propagation of pressure pulse along the artery. In our previous work, we researched methods to adapt cuff modulation techniques for pulse transit time vs. BP calibration and for measurement of other hemodynamic indices of potential interest to critical care, such as arterial compliance.