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01 g/min (3.93-4.25 g/min). These two parameters were statistically and significantly different in all the 4 groups (p 0.05). HoLEP still has a steep learning curve. It is necessary to reach the number of cases of 25-50 to reach fundamental experience. HoLEP still has a steep learning curve. It is necessary to reach the number of cases of 25-50 to reach fundamental experience. To review the evidence concerning treatment-related gynecomastia in patients taking spironolactone, antiandrogens, 5 alpha-reductase inhibitors, lipid-lowerin