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Results In both the early and late treatment groups, DIZE significantly attenuated the mean pulmonary artery pressure, pulmonary arteriolar remodeling, and right ventricle brain natriuretic peptide (BNP), as well as reversed the overexpression of ACE while up-regulating the expression of Ang-(1-7) when compared with the vehicle-treatment group. In addition, the early treatment group also significantly decreased plasma BNP and increased the expression of eNOS. Conclusions ACE2 activator has therapeutic potentials for preventing and a

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olo_da_erysiphe_corylacearum.pdf Sezer AD et al. 2017. Phytoparasitica, 45, 577-581. Voglmayr H et al. 2020. New Disease Reports, 42, 14 http//dx.doi.org/10.5197/j.2044-0588.2020.042.014.Repeated sampling conducted from December 2019 to March 2020, and fruit of pineapple (Ananas comosus) var MD2 showing early stem end rot symptoms including brown and rotten fruit skin near the stem end region (Fig.1Aa) or darker skin with black discoloration (Fig.1Ab) indicated a consistent fungal infection. The samples (30 fruits from each location) w