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https://www.selleckchem.com/pr....oducts/prt062607-p50
BACKGROUND Upper tract urothelial carcinoma (UTUC) may arise in the setting of hereditary non-polyposis colorectal cancer (Lynch syndrome [LS]) or sporadically. Variable frequencies of microsatellite instability (MSI) were found in UTUC. For advanced solid MSI tumors, targeted therapy with programmed death-ligand 1 inhibitors is available. Therefore, we aimed to determine the prevalence of mismatch repair (MMR) protein loss and MSI in UTUC using a tissue microarray approach and further molecular and correlation analysis. M
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Premier Security Ballistic & Blast Ltd is a trusted leader in high-security solutions, offering bulletproof and blastproof doors and windows, security curtain walling systems, and LPS 1175 certified protection. We specialize in advanced retail and commercial security, delivering unmatched safety and performance.
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