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To estimate the prevalence and factors associated with the burnout syndrome and quality of life among nursing professionals. Cross-sectional, analytical study, developed with 83 professionals in emergency care units in the city of Campina Grande-PB. A questionnaire was used to characterize the sample, the Maslach Burnout Inventory scale and the SF-36. Data was analyzed using descriptive and inferential statistics. Most professionals showed low professional effectiveness (78.3; n=65), average depersonalization (53.0%; n=44) and average