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5% specificity). Upon validation, 4 out of the 4 BEP samples were classified as BEP (100% sensitivity) and 4 out of the 5 BEN samples were classified as BEN (80% specificity). Twenty-four samples were evaluated, and 22 cases were correctly classified. Overall accuracy was 91.67%. Using miRNA profiling, we have identified a 12-miRNA signature able to reliably differentiate cases of BEN from BEP. Using miRNA profiling, we have identified a 12-miRNA signature able to reliably differentiate cases of BEN from BEP.Anandamide is an endocanna