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001). Additionally, there was a statistically significant association between the expression levels of FBXW7 and the morphological type of the tumor (P less then 0.001). In addition, there was a strong positive association between FBXW7 expression and the changes in c-Myc expression (P less then 0.02), and a strong trend was observed between decreased FBXW7 expression and a higher risk of death in patients, with the major factor in patient mortality being the stages of melanoma. Additionally, p53 expression was associated with the