Few things are as uplifting as the sight of sunflowers. Symbolizing adoration, loyalty, and longevity, a #birthdayflowerbouquet featuring these sunny blooms is the perfect way to wish someone a happy year ahead. Sunflowers have an innate ability to turn heads and spark smiles, making them a fantastic choice for summer birthdays or for anyone who brings light into your life. At Blossoms and Bloom, we pair our radiant sunflowers with complementary textures to create dynamic and eye-catching displays. A birthday flower bouquet rich with yellows and greens acts as a beacon of happiness, instantly brightening up any space. It is a gift that says, "I hope your year is as bright and beautiful as you are." Celebrate their existence with the raw, natural beauty of these iconic flowers.

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Key points• Fundamental properties of various ribose-5-phosphate isomerases (Rpis).• Differences in crystal structure and catalytic mechanism between RpiA and RpiB.• Application of Rpi as a rare sugar producer and a potential drug target.Background Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whether ascites was a fa