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Such interpretation actually constitutes the main time-consuming part of tomography and is less amenable to automation compared to the initial reconstruction. The mechanism of fetal growth restriction (FGR) is not fully understood. In this study, we explored the contribution of the calpain-calpastatin system and the activated states of calpains in human FGR placenta. The placentas were collected from patients of FGR (n=17) and controls (n=23) at elective cesarean sections in Nagoya City University Hospital and used for experiments upon