https://www.selleckchem.com/pr....oducts/eidd-2801.htm
Prevention of aberrant cutaneous wound repair and appropriate regeneration of an intact and functional integument requires the coordinated timing of fibroblast and keratinocyte migration. Here, we identified a mechanism whereby opposing cell-specific motogenic functions of a multifunctional intracellular and extracellular protein, receptor for hyaluronan-mediated motility (RHAMM), coordinates fibroblast and keratinocyte migration speed and ensures appropriate timing of excisional wound closure. We found that, unlike in wildtype mice,
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