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We suggest PLAID, APLAID, and FCAS3 have to be considered as different aspects of the same underlying condition, because of our long-term clinical and genetical experiences. Some CVID patients have the same disease-causing mutations in PLCG2 gene, so it may be better to define all of them as "PLCG2deficiency."Necrotizing sialometaplasia can make anyone very anxious about the lesion especially if they have habit of tobacco consumption. It requires a prompt diagnosis, counseling with assurance to patient and treatment.Involvement of the e
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