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production seems plausible as the predominant point source for the global M. chimaera outbreak. Although HCDs can be contaminated with mixed populations, M. chimaera strains of the subgroup 1.1 caused most infections. Data on the clinical and demographic features of Canadian patients with hereditary angioedema (HAE) are lacking. To describe the clinical and demographic features in a large Canadian HAE cohort and compare them with patients with HAE in other countries. An online questionnaire was distributed to the members of 2 Canadian HAE patient gr