https://www.selleckchem.com/pr....oducts/LDE225(NVP-LD
Enhanced aerobic glycolysis is a motivation of fibroblast-myofibroblast transdifferentiation (FMT), leading to kidney fibrosis. 3-Bromopyruvate (3-BrPA) is a glycolysis inhibitor and has fibrosis-protected effect in liver. This study aims to explore the effects of 3-BrPA on aerobic glycolysis and kidney fibrosis in a unilateral ureteral obstruction (UUO) mice model and transforming growth factor-β1(TGF-β1)-stimulated normal rat kidney fibroblast (NRK49F) cell model in vitro. In vivo UUO mouse model and in vitro TGF-β1 stimula

https://hays-holck-3.technetbl....oggers.de/how-to-tra
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