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Trans-synaptic cell-adhesion molecules are critical for governing various stages of synapse development and specifying neural circuit properties via the formation of multifarious signaling pathways. Recent studies have pinpointed the putative roles of trans-synaptic cell-adhesion molecules in mediating various cognitive functions. Here, we review the literature on the roles of a diverse group of central synaptic organizers, including neurexins (Nrxns), leukocyte common antigen-related receptor protein tyrosine phosphatases (LAR-RPTPs), and

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How an Upgrade Item Affects a Pokemon's Stats An introduction paragraph is a crucial part of an essay. It introduces the topic the essay will tackle and encourages readers to continue reading. It should also provide valuable context, such as background information on existing perspectives and cultural attitudes. Upgrades are items that can be used to evolve Porygon into Porygon2 when traded or using a link cable. They can be obtained by spinning a Pokestop's picture disc, or as a rare reward from special events. Affects the stats of Pokemo